Reducing In-Stent Restenosis
نویسندگان
چکیده
All animal procedures were performed in accordance with UK Home Office Guidance on the operation of the Animals (Scientific Procedures) Act 1986 and institutional ethical approval (PPL60/4114 and PPL 60/4429). Male white Landrace pigs (SAC Commercial Ltd, Edinburgh, UK) and miR-21 knockout mice (1) were maintained on a 12 hour light/dark cycle with free access to food and water at a designated Biological Procedures Unit prior to stenting and maintained for a period of 7 or 28 days thereafter. Stented Human coronary arteries were dissected from explanted hearts at the time of cardiac transplantation. All procedures had local ethical approval (Research Ethical Committee number: 06/S0703/110) and experimental procedures conformed to the principles outlined in the Declaration of Helsinki.
منابع مشابه
Overview of Intracoronary Brachytherapy for in-Stent Restenosis of a Drug-Eluting Stent
Percutaneous coronary intervention with stenting is considered recently as the most common procedure for the treatment of symptomatic coronary. The article reviewed 41 studies published during 1997-2019 on intracoronary brachytherapy for in-stent restenosis of a drug-eluting stent. Intracoronary radiation therapy was finally confirmed in the setting of in-stent restenosis using as adjunctive th...
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In-stent restenosis (ISR) is regarded as the main problem in the utilization of stents in the treatment of coronary artery atherosclerotic stenosis in percutaneous coronary intervention (PCI). This study investigated the possible role of the G22A variant of the Adenosine Deaminase gene (ADA) in the development of ISR. In this study, 91 patients who underwent PCI were divided into two groups of ...
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